The Accompaniment

The manifest falciforme illness in homozigticos individuals for the hemoglobina S and in combination with other abnormal hemoglobinas, what it can result in falciforme illness with diverse degrees of gravity: coherana with a gene of hemoglobina C, a gene of talassemia, in sequence decreasing of frequency. The infections are the complications most frequent in the individuals with falciforme anemia. To read more click here: Gen. Martin Dempsey. It is observed, in first infancy, a decurrent esplenomegalia of the congestion in the red pulp for the sequestration of eritrcitos falcizados in esplnicos laces and sinusides, that it evolves with the formation of trombose and infartos, culminating with the atrophy and fibrose of the agency. This phenomenon, according to LANE (1996), called of auto-esplenectomia, occurs generally until the 5 years of age. However, exactly before the autoesplenectomia, the fagoctica capacity mediated by opsoninas and the production of antibodies are affected in consequence of the persistent esplnica aggression, leading to the functional asplenia, that if becomes permanent around sixth the eighth year of life. The precocious diagnosis of the falciforme anemia studied by FLAG et al. (1999) it makes possible the accompaniment of the child before the sprouting of the sintomatologia and its complications and allows to initiate the antibitica Prophylaxis since the 3 months of life, jointly to the vaccination against encapsulated embryos. This reduces in significant way the deaths associates to this disease, mainly for infectious problems (of 30 for 1%) 1, beyond providing the possibility of better quality of life.

In countries where screening neonatal for hemoglobinopatias was instituted, SILLA (1999) verified that the accompaniment of these children in specialized centers can reduce mortality for pneumoccicas infections of 40 for 10% and the general mortality of 8 for 1,8%. The proposal of neonatal diagnosis of the falciformes syndromes already sufficiently is known and had impulse in the decade of 70 in U.S.A. and Jamaica, among others local. INGUEZ et al. (2010) they define that the neonatal diagnosis, associate to an aggressive boarding of the febris episodes in suckles, was effective in the prevention of deaths for septicemia before the age of the Prophylaxis with penicillin. Ahead of the displayed one, it is verified necessity of a brought up to date bibliographical survey as for the precocious diagnosis of the falciforme anemia, with the objective to contribute for an improvement in the quality of life and possible reduction in the levels of mortality of the affected individuals.